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how to get zepbound is the same medication as Mounjaro (tirzepatide) but is specifically FDA-approved for chronic weight management in adults with obesity or overweight (BMI ≥27) with at least one weight-related condition (e.g., hypertension, type 2 diabetes). It was approved in November 2023 as Eli Lilly’s dedicated anti-obesity brand for tirzepatide.
Key Differences from Mounjaro
Feature | Zepbound | Mounjaro |
---|---|---|
FDA Approval | Chronic weight management (Nov 2023) | Type 2 diabetes (May 2022) + off-label weight loss |
Indication | Obesity/overweight + comorbidities | Type 2 diabetes (primary) + weight loss |
Insurance Coverage | Often limited for weight loss (varies by plan) | More likely covered for diabetes management |
Dosage for Weight Loss how to get zepbound
Same as Mounjaro:
- Start: 2.5 mg once weekly for 4 weeks (to reduce GI side effects).
- Titrate: Increase by 2.5 mg every 4 weeks (5 mg → 7.5 mg → 10 mg → 12.5 mg → 15 mg).
- Maintenance: Effective doses for weight loss are typically 10 mg, 12.5 mg, or 15 mg.
Weight Loss Efficacy how to get zepbound
- In the SURMOUNT-1 trial, non-diabetic participants lost 18–22% of baseline weight at 72 weeks (vs. 2–3% with placebo).
- In SURMOUNT-2 (participants with type 2 diabetes), average weight loss was ~13–15%.
Who Should Take Zepbound? how to get zepbound
- Adults with obesity (BMI ≥30) or overweight (BMI ≥27 + weight-related condition).
- Patients seeking sustained weight loss alongside diet/exercise changes.
- Not for use in:
- Pregnancy or breastfeeding.
- Personal/family history of medullary thyroid cancer (MTC) or MEN2 syndrome.
- Severe gastrointestinal disease (e.g., gastroparesis).
Cautions
- Boxed Warning: Risk of thyroid C-cell tumors (seen in animal studies; human relevance unknown).
- Other Risks: Pancreatitis, gallbladder disease, hypoglycemia (if combined with insulin/sulfonylureas), acute kidney injury, and suicidal behavior/thinking (rare reports).
- Avoid in pregnancy; use contraception during treatment.
Side Effects
- Most Common (~30% of users): Nausea, diarrhea, vomiting, constipation, indigestion.
- Serious (Rare): Pancreatitis, gallstones, ileus (intestinal blockage), allergic reactions.
- Side effects often improve with dose escalation and over time.
Why Choose Zepbound?
- Dual-action drug: Targets GLP-1 and GIP receptors for stronger appetite suppression and metabolic benefits.
- Superior weight loss: Outperforms semaglutide (Wegovy) in trials.
- Additional benefits: Improves blood pressure, cholesterol, and blood sugar control.
Cost and Accessibility
- List price: ~$1,060/month (similar to Mounjaro).
- Savings: Eli Lilly offers a manufacturer coupon (reduces cost to ~$550/month for eligible insured patients).
- Insurance: Coverage is expanding but remains limited for weight-loss drugs; prior authorization often required.
Key Considerations
- Prescription required: Must be prescribed by a clinician familiar with obesity management.
- Lifestyle changes: Works best with a reduced-calorie diet and increased physical activity.
- Long-term use: Obesity is a chronic condition; indefinite treatment may be needed to maintain weight loss.
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Zepbound is a breakthrough option for obesity treatment but requires careful monitoring for safety and efficacy. Always consult your healthcare provider to determine if it aligns with your health goals.
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